Salman Khan

发布时间:2024-01-08  作者:  点击量:



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Salman Khan

Post-doctor

Email: salmankhan(AT)nbu.edu.cn




Research Expertise

• Isolation of natural products from deep-sea derived fungi, actinomycetes, plants and their structure elucidation by (HPLC, LCMS, NMR, IR, UV, X-RAY).

• Synthetic biology and metabolic engineering.

• Screening of sub-seafloor fungi for isolation of new and novel bioactive compounds.

• Natural products biosynthesis-pathway discovery and elucidation.

• Agroinfiltration using N. benthamianna transient expression system for high yield of triterpenoids.

• Metabolomics.

• Optimization of fermentation media for bioactive compound production.

• Bioactivities of bioactive natural compounds (Antibacterial, Antifungal, Cytotoxic, Enzyme assays, antiparasitic, etc).

• Skills of writing scientific reports, projects, research papers, proofreading, and correction of manuscripts and documentation.


Personal Brief Introduction

I hold a PhD in Pharmacy from Nanjing University, China, and bring extensive postdoctoral experience from Southern University of Science and Technology (SUSTech) in Shenzhen. Driven by a competitive spirit, I am committed to achieving excellence and advancing scientific knowledge.


Education Experience

2009.09-2014.09

Gomal University, Pakistan - Pharm.D (Doctor of Pharmacy)

2015.09-2017.09

Khyber Medical University, Pakistan - M.Phil in Pharmacology

2018.09-2022.09

Nanjing University, China - PhD in Pharmacy

2022.08-2024.08

Southern University of Science and Technology (SUSTech), Shenzhen China – Postdoctoral Research Fellow

2024.10-Present

Ningbo University, China, Institute of Drug Discovery Technology, Postdoctoral Research Fellow


 Research Paper Published

1. Xie J, Tian J, Salman Khan, Chen F, Hao Y, Xiong HM, Zhang F, Zhou Q, Zhu GY, Huang AC. Glyceollin biosynthesis in a plant chassis engineered for isoflavone production. Nature Chemical Biology. 2025. DOI: 10.1038/s41589-025-01914-3.

2. Salman Khan, Wang T, Ul Arifeen MZ, Huang S. Exploring the bioactive potential of deep-sea microorganisms: A review of recent discoveries. Bioorganic Chemistry. 2025.  doi.org/10.1016/j.bioorg.2025.108521.

3. Zhao EJ, Salman Khan, Guo H, Sun JL, Zhu A, Jiao RH, Ge HM, Zhang B. A Two-Enzyme Cascade Directing Polycyclic Assembly in Tetrodecamycin Biosynthesis. Organic Letters. 2025. doi.org/10.1021/acs.orglett.5c01652.

4. Liu YY, Wei TT, Ran GJ, Li XH, Salman Khan, Cai T, Lai CT, Wang HK, Wu B, Jin HX, Zhang WY, Wang TT, He S. α-Pyrones, Root Growth Inhibitors from a Mesophotic Zone Sponge-Associated Fungus Purpureocillium sp. NBUF263. Phytochemistry Letters.      2025. doi.org/10.1016/j.phytol.2025.102944.

5. Wei TT, Li J, Zheng Q, Liu Y, Ran GJ, Ding H, Huang S, Salman Khan, Wu B, He S, Wang TT. HSQC-TOCSY fingerprinting-guided isolation of undescribed glycosides and scalemic pentaketides with neuroprotective activity from a mesophotic zone Ircinia sponge-associated fungus, Acremonium sp. NBUF233. Fitoterapia. 2025. doi.org/10.1016/j.fitote.2025.106856.

6. Salman Khan, ZHU H-J, SUN Z-Q, Li Y-L, WANG L, WANG R, GUO Z-K, JIAO R-H. Isolation and Biological Activity of Seven New Drimane-Type Sesquiterpenoids from an Earwig-Associated Aspergillus sp. NF2396. Chin J Nat Med. 2022;20(0):1-7. doi: 10.1016/S1875-5364(22)60203-6.

7. 焦瑞华、Salman Khan、童志武、史净。 ⼀种新型II型聚酮化合物 Actketone及其制备⽅法和应⽤(国家发明专利号202210537584.0)Jiao RH, Salman Khan, Tong ZW, Shi J). A new type II polyketone compound Actketone and its preparation method and application. National Invention Patent No.  202210537584.0.

8. Tong ZW, Wang TT, Yang P, Sun JL, Zhang CP, Salman Khan, Wang XC, Jiao RH, Ge HM, Zhuang WY, Hu G, Tan RX. Acatulides A−G, neuroprotective macrolides from Acaulium album H-JQSF. Chinese Chemical Letters. 2023.

9. Guo Z, Ma S, Salman Khan, Zhu H, Zhang B, Zhang S, Jiao R. Zhaoshumycins A and B, Two Unprecedented Antimycin-Type Depsipeptides Produced by the Marine-Derived Streptomyces sp. ITBB-ZKa6. Marine Drugs. 2021;19(11):624.

10. Li W, Jiao FW, Wang JQ, Shi J, Wang TT, Salman Khan, Jiao RH, Tan RX, Ge HM. Unguisin G, a new  kynurenine-containing cyclic heptapeptide from the sponge-associated fungus Aspergillus candidus NF2412. Tetrahedron Letters. 2020;61(40):152322.

11. Shah AA, Qian C, Wu J, Liu Z, Salman Khan, Tao Z, Zhang X, Khan IU, Zhong X. Effects of natamycin and Lactobacillus plantarum on the chemical composition, microbial community, and aerobic stability of Hybrid pennisetum at different temperatures. RSC Advances. 2020;10(15):8692-702.

12. Ahmad S, Ali W, Salman Khan, Ul Arifeen MZ. Heavy metal contamination and health risks assessment in soil-rice system irrigated with wastewater in northern Pakistan. (2024). Preprint. DOI: 10.21203/rs.3.rs-5319547/v1.


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