吴翊乐

发布时间:2025-02-27  作者:  点击量:

 

 

吴翊乐 博士

研究员

Email:wuyile(AT)nbu.edu.cn

个人主页:https://orcid.org/0000-0002-8450-5254

                 https://www.x-mol.com/groups/stephan

研究领域/兴趣:

磷化学




个人简介:

主要研究领域为磷化学及其应用。以磷化学为基础,研究相关小分子活化与转化、药物的合成以及生命有机分子的起源。担任《化学试剂》杂志青年编委,作为骨干成员承担和参与了多项国家级、省部级科研项目。发表SCI论文40余篇,获批专利4项,担任多个杂志审稿人。

ORCID: 0000-0002-8450-5254


教育与科研经历:

2007-20011

厦门大学化学系,理学学士

2011-2016

厦门大学化学系,理学博士(导师:赵玉芬 院士)

2017-2019

香港中文大学化学系,博士后(导师:谢作伟 院士)


2020-2024

宁波大学新药技术研究院,副研究员


2024-至今

宁波大学新药技术研究院,研究员


代表性论文:

<以宁波大学新药技术研究院为第一单位>

1. Ju, S.; Tan, J.; Chen, T. *; Yan, W.; Xi, N.; Stephan, D. W.*; Wu, Y.*   Superacidic Aluminum Azido Species: Precursor to Triazolyl Dimers, Trimers and Tetramers  Inorg. Chem. Front., 2025, DOI: 10.1039/D5QI00038F

2. Tang, B.; Ju, S.; Yan, W.; Chen, T.; Stephan, D. W.*; Wu, Y.* Reactivity of N-(isocyanoimino)triphenylphosphorane toward group 13 Lewis acids Chem. Commun., 2024, 60, 12932-12935

3. Ju, S.; Zhang, C.; Tang, B.; Liu, L.; Stephan, D. W.*; Wu, Y.* The Lewis superacidic aluminium cation: [(NHC)Al(C6F5)2]+, Chem. Commun., 2024, 60, 698-701;

4. Luo, Y.-A.; Zhao, Z.; Chen, T.; Li, Y.; Zhao, Y.; Stephan, D. W.*; Wu, Y.* Stannyl phosphaketene as a synthon for phosphorus analogues of β-lactam, Chem. Commun., 2023, 59, 10956-10959;

5. Chen, T.; Ju, S.; Tong, M.; Zhao, Y.; Wu, Y.*, Stephan, D. W.* Synthesis and characterization of phosphate-catecholate chelated Nd(III), Zr(IV) and Al(III) complexes, Eur. J. Inorg. Chem., 2023, e202300443 (Invited contribution in the special collection of "Chinese EurJIC Talents");

6. Hussain, Z.; Luo, Y.-A.; Wu, Y.*; Qu, Z.-W.*; Grimme, S.; Stephan, D. W.* Reactivity of frustrated Lewis pairs with BOC protected diazocarboxylates: FLP capture of diazene, Chem. Commun., 2023, 59, 6191-6194;

7. Hussain, Z.; Luo, Y.-A.; Wu, Y.*; Qu, Z.-W.*; Grimme, S.; Stephan, D. W.* Diazene Chemistry: Metal-Free Models of N2 Reduction Intermediates,  J. Am. Chem. Soc. 2023, 145, 7101-7106;

8. Chen, T.; Mei, Y.; Liu, L. L.*; Zhao, Y.; Wu, Y.*; Stephan, D. W.* Alkoxyphosphorane /Borane Cooperative alkylations: A Frustrated Lewis Pair Version of the Mitsunobu Reaction, Chem. Eur. J. 2023, 29, e202300264;

9. Mandal, D.; Hussain, Z.; Luo, Y.-A.; Wu, Y.*; Stephan, D. W.* Transient Hydroboration and hydroalumination of activated azo-species: Avenues to NBO and NAlO-heterobicycles, Chem. Commun., 2023, 59, 780-783;

10. Tan, J.; Hu, C.; Yang, X.; Ju, S.; Cao, L.; Wu, Y.*; Liu, L. L.*; Stephan, D. W.* Structure and reactivity studies of the aluminum analogue of Piers' borane [HAl(C6F5)2]3, Chem. Commun., 2023, 59, 282-285;

11. 谭敬杰, 罗永安, 吴翊乐*, 赵玉芬*. Piers硼烷的应用研究进展. 化学试剂, 2023, 45, 1-11;

12. Zhao, Z.; Tan, J.; Chen, T.; Hussain, Z.; Li, Y.; Wu, Y.*; Stephan, D. W.* Ambiphilic Behavior of Ge(II)-Pseudohalides in Inter- and Intramolecular Frustrated Lewis Pair Alkyne Addition Reactions,  Inorg. Chem. 2022, 61, 18670-18677;

13. Wu, Y.*; Zhao, Z.; Chen, T.; Tan, J.; Qu, Z.-W.*; Grimme, S.; Zhao, Y.; Stephan, D. W.* The varied frustrated Lewis pair reactivity of the germylene phosphaketene (CH{(CMe)(2,6-iPr2C6H3N)}2)GePCO, Chem – Eur. J. 2022, 28, e202200666;

14. Yang, X.; Wei, R.; Shi, Y.; Liu, L. L.; Wu, Y.*; Zhao, Y.; Stephan, D. W.* Oxyphosphoranes as precursors to bridging phosphate-catecholate ligands, Chem. Commun. 2021, 57, 1194-1197.


 专利成果:

一种有机硼酸酯化合物的制备方法, ZL 201611113351.9.

一种手性氨基酸的检测方法, ZL 202210008922.1

一种有机铝氢试剂的合成方法和应用, ZL202210580187.1


 

 

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